The FBI in Peace and War is a captivating radio crime drama series that aired on CBS from November 25, 1944 to September 28, 1958, bringing to life the relentless pursuit of criminals by the Federal Bureau of Investigation. Inspired by Frederick Lewis Collins' book of the same name, the show presents an innovative narrative approach, as it delves into the minds and actions of wrongdoers while they commit their crimes.

The storylines often focus on various non-violent offenses such as robbery and interstate car theft, providing the audience with a unique, gritty perspective on law enforcement. Listeners follow Field Agent Sheppard, portrayed by William Blaine, as he tracks down and apprehends criminals. Over the years, the radio show was sponsored by Lava Soap, Wildroot Cream-Oil, Lucky Strike, Nescafe, and Wrigley's, and was once ranked the eighth most popular show on radio according to Time.

Produced and directed by Max Marcin and Betty Mandeville, the show's scripts capture authentic elements of crime-solving, with writing contributions mainly from Louis Pelletier, as well as Jack Finke, Ed Adamson, and Collins. The cast also features Donald Briggs and the voice talents of Lisa Loughlin (from 1952) and Alice Frost. Although the program disclaimed any official Bureau endorsement, it intriguingly claimed that its stories were based on real-life FBI cases.