Crime and Peter Chambers is an American old-time radio detective program that aired on NBC from April 6, 1954, to September 7, 1954. The show was based on the character Peter Chambers, a hard-hitting private detective created by author Henry Kane, who also wrote the scripts and directed the show. Unlike many private detectives on radio, Chambers coordinated his work with the police and had a close relationship with his best friend, Lt. Louis Parker, played by Bill Zuckert.

The series starred Dane Clark as Peter Chambers, a playboy detective with an eye for solving crime and a taste for beautiful women. The show was known for its glib dialogue that played into Clark's reputation as a screen tough guy. A total of 21 episodes from the series are available. Other actors involved in the show include Fran Carlon, Roger DeKoven, and William Griffis, among others. Crime and Peter Chambers was short-lived, lasting only five months; however, it remains a notable piece of radio detective history.