The Abbott and Costello Show was a popular American comedy radio program that aired from 1940 to 1949, initially on NBC and later on ABC. The 30-minute weekly show featured the comedic duo of film stars Bud Abbott and Lou Costello, who brought their vaudeville-style skits to the radio format, often focusing on their attempts to succeed in various business ventures.

The show featured a talented supporting cast, including Joe Kirk, Artie Auerbach, Elvia Allman, Iris Adrian, Mel Blanc, and more. Notable guest stars included Cary Grant, Frank Sinatra, the Andrews Sisters, and Lucille Ball. The program also showcased singers such as Amy Arnell and Connie Haines, with orchestra leaders like Skinnay Ennis, Charles Hoff, and Peter van Steeden providing music.

Abbott and Costello began their radio career on Kate Smith's program in 1938 before getting their own show in 1940. Throughout the 1940s, they became one of the top radio comedy acts, famous for their rapid-fire wordplay and hilarious confusion, particularly in classic routines like "Who's on First?". Bud Abbott (born 1895) and Lou Costello (born 1906) first teamed up in 1935 at the Eltinge Burlesque Theater in New York and went on to leave a lasting impact on comedy through their radio and television work.